diff --git a/packages/flutter/lib/src/material/list_tile.dart b/packages/flutter/lib/src/material/list_tile.dart
index 81f1b63e77..efa192621c 100644
--- a/packages/flutter/lib/src/material/list_tile.dart
+++ b/packages/flutter/lib/src/material/list_tile.dart
@@ -1484,18 +1484,36 @@ class _RenderListTile extends RenderBox
     final Size? leadingSize = leading == null ? null : getSize(leading, iconConstraints);
     final Size? trailingSize = trailing == null ? null : getSize(trailing, iconConstraints);
 
-    assert(
-      tileWidth != leadingSize?.width || tileWidth == 0.0,
-      'Leading widget consumes entire tile width. Please use a sized widget, '
-      'or consider replacing ListTile with a custom widget '
-      '(see https://api.flutter.dev/flutter/material/ListTile-class.html#material.ListTile.4)',
-    );
-    assert(
-      tileWidth != trailingSize?.width || tileWidth == 0.0,
-      'Trailing widget consumes entire tile width. Please use a sized widget, '
-      'or consider replacing ListTile with a custom widget '
-      '(see https://api.flutter.dev/flutter/material/ListTile-class.html#material.ListTile.4)',
-    );
+    assert(() {
+      if (tileWidth == 0.0) {
+        return true;
+      }
+
+      String? overflowedWidget;
+      if (tileWidth == leadingSize?.width) {
+        overflowedWidget = 'Leading';
+      } else if (tileWidth == trailingSize?.width) {
+        overflowedWidget = 'Trailing';
+      }
+
+      if (overflowedWidget == null) {
+        return true;
+      }
+
+      throw FlutterError.fromParts(<DiagnosticsNode>[
+        ErrorSummary(
+          '$overflowedWidget widget consumes the entire tile width (including ListTile.contentPadding).',
+        ),
+        ErrorDescription(
+          'Either resize the tile width so that the ${overflowedWidget.toLowerCase()} widget plus any content padding '
+          'do not exceed the tile width, or use a sized widget, or consider replacing '
+          'ListTile with a custom widget.',
+        ),
+        ErrorHint(
+          'See also: https://api.flutter.dev/flutter/material/ListTile-class.html#material.ListTile.4',
+        ),
+      ]);
+    }());
 
     final double titleStart =
         leadingSize == null
diff --git a/packages/flutter/test/material/list_tile_test.dart b/packages/flutter/test/material/list_tile_test.dart
index 85127ad0ca..ab5fb5313a 100644
--- a/packages/flutter/test/material/list_tile_test.dart
+++ b/packages/flutter/test/material/list_tile_test.dart
@@ -2618,6 +2618,36 @@ void main() {
     expect(trailingOffset.dy - tileOffset.dy, topPosition);
   });
 
+  testWidgets('Leading/Trailing exceeding list tile width throws exception', (
+    WidgetTester tester,
+  ) async {
+    Widget buildListTile({Widget? leading, Widget? trailing}) {
+      return MaterialApp(
+        home: Material(
+          child: Center(
+            child: SizedBox(width: 100, child: ListTile(leading: leading, trailing: trailing)),
+          ),
+        ),
+      );
+    }
+
+    // Test a trailing widget that exceeds the list tile width.
+    // 16 (content padding) + 61 (leading width) + 24 (content padding) = 101.
+    // List tile width is 100 as a result, an exception should be thrown.
+    await tester.pumpWidget(buildListTile(leading: const SizedBox(width: 61)));
+
+    // Error message cannot be tested as there too many errors thrown.
+    expect(tester.takeException(), isNotNull);
+
+    // Test a trailing widget that exceeds the list tile width.
+    // 16 (content padding) + 61 (trailing width) + 24 (content padding) = 101.
+    // List tile width is 100 as a result, an exception should be thrown.
+    await tester.pumpWidget(buildListTile(trailing: const SizedBox(width: 61)));
+
+    // Error message cannot tested be as there too many errors thrown.
+    expect(tester.takeException(), isNotNull);
+  });
+
   group('Material 2', () {
     // These tests are only relevant for Material 2. Once Material 2
     // support is deprecated and the APIs are removed, these tests